EXPERIMENTAL AND MOLECULAR DYNAMIC STUDY OF GRAIN REFINEMENT AND DISLOCATION SUBSTRUCTURE EVOLUTION IN HSLA AND IF STEELS AFTER SEVERE PLASTIC DEFORMATION

Experimental and Molecular Dynamic Study of Grain Refinement and Dislocation Substructure Evolution in HSLA and IF Steels after Severe Plastic Deformation

In this study, large-scale molecular dynamic simulations were performed to analyze the dislocation substructure interaction with various types of obstacles present in microalloyed steels during severe plastic deformation.Specifically, fully functional numerical models of the atomic upsetting test were developed, with particular emphasis on the pres

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Practical aspects of chimeric antigen receptor T-cell administration: From commercial to point-of-care manufacturing

Chimeric antigen receptor T-cells targeting the CD19 antigen have achieved impressive results in patients with relapsed/refractory (R/R) B-cell malignancies, leading to their approval in the European Union and other jurisdictions.In Spain, the 100% academic anti-CD19 CART-cell product varnimcabtagene autoleucel (var-cel, ARI-0001 cells) has been ex

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Reconsidering Representation in College Design Curricula

The Future of Design Education working group on representation addressed the roles of data, maps, models, Sponges and interfaces as a continuum from representation to action.The article traces historical ideas of representation grounded by a linguistic paradigm to more recent approaches based on performance, embodiment, and sensory modalities other

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